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North America (East Coast) → North America (West Coast)Any month · Edit search

50 Panama Canal voyages from North America’s East Coast to North America’s West Coast

Panama Canal voyages, soonest first. Fares are per person, from the lowest cabin.

Voyages by month
  1. Fort Lauderdale Los Angeles Sapphire Princess · Princess Cruises · 16 nights Via Port of Oranjestad, Puntarenas and Puerto Vallarta from $999$62 / night
  2. Miami San Diego Norwegian Star · Norwegian Cruise Line · 16 nights Via Cartagena, Puntarenas and Cabo San Lucas suites from $8,489$531 / night
  3. Fort Lauderdale Los Angeles Island Princess · Princess Cruises · 16 nights Via Port of Oranjestad, Puntarenas and Puerto Vallarta from $1,249$78 / night
  4. Miami San Francisco Azamara Quest · Azamara · 18 nights Via Cabo Rojo, Puntarenas and San Diego from $2,869$159 / night
  5. Miami San Diego Zuiderdam · Holland America Line · 14 nights Via Cartagena, Puerto Quetzal and Cabo San Lucas from $1,199$86 / night
  6. Fort Lauderdale San Diego Zaandam · Holland America Line · 14 nights Via Cartagena, Puerto Quetzal and Cabo San Lucas from $1,399$100 / night
  7. Miami Los Angeles Brilliant Lady · Virgin Voyages · 16 nights Via Cartagena, Puntarenas and Cabo San Lucas from $2,064$129 / night
  8. Mobile Seattle Carnival Spirit · Carnival Cruise Line · 16 nights Via Cartagena, Panama Canal and Cabo San Lucas from $911$57 / night
  9. Fort Lauderdale Los Angeles Star Princess · Princess Cruises · 16 nights Via Port of Oranjestad, Fuerte Amador and Cabo San Lucas from $1,584$99 / night
  10. Fort Lauderdale San Diego Eurodam · Holland America Line · 14 nights Via Cartagena, Puntarenas and Puerto Vallarta from $1,724$123 / night
  11. Fort Lauderdale Vancouver Eurodam · Holland America Line · 20 nights Via Cartagena, Puerto Quetzal and San Francisco from $2,104$105 / night
  12. Tampa Seattle Carnival Legend · Carnival Cruise Line · 16 nights Via Santa Marta, Panama Canal and Cabo San Lucas from $1,076$67 / night
  13. Miami Seattle MSC Poesia · MSC Cruises · 18 nights Via Cartagena, Huatulco and Los Angeles from $1,557$86 / night
  14. Miami Seattle MSC Poesia · MSC Cruises · 25 nights Via Cartagena, San Diego and Victoria from $3,807$152 / night
  15. New York Seattle Norwegian Bliss · Norwegian Cruise Line · 22 nights Via Puerto Plata, Puerto Quetzal and Victoria from $2,659$121 / night
  16. New York San Francisco Norwegian Bliss · Norwegian Cruise Line · 19 nights Via Puerto Plata, Puerto Caldera and Cabo San Lucas from $2,439$128 / night
  17. Fort Lauderdale Vancouver Nieuw Amsterdam · Holland America Line · 21 nights Via Port of Oranjestad, Puerto Quetzal and Victoria from $2,099$100 / night
  18. Miami Los Angeles EXPLORA III · Explora Journeys · 21 nights Via Ocho Rios, Cartagena and Puerto Vallarta suites from $17,885$852 / night
  19. Tampa Los Angeles Celebrity Summit · Celebrity Cruises · 15 nights Via Georgetown, Colon and Puerto Vallarta from $1,745$116 / night
  20. Fort Lauderdale Los Angeles Island Princess · Princess Cruises · 16 nights Via Port of Oranjestad, Puntarenas and Puerto Vallarta from $1,639$102 / night
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